Apparatus for removing liquid contents of a container

ABSTRACT

Cradles for draining liquid from containers are described herein. An example apparatus includes a housing having a bottom wall, a side wall and an open top. The housing is to receive a container having liquid. The example apparatus includes a probe extending upward from the bottom wall toward the open top and is to drain the liquid from the container when the probe is inserted into the container. The example apparatus also includes a sliding lock slidably disposed within the housing that receives a cap or top of the container when the container is inserted into the housing. The sliding lock includes a key slot. The sliding lock is movable when a cap or top of the container has a matching key that engages the key slot, which enables the sliding lock to move downward to expose the probe and drain the liquid from the container.

RELATED APPLICATION

This application claims the benefit under 35 U.S.C. §119(e) to U.S.Provisional Application No. 62/155,768, titled “Apparatus for RemovingLiquid Contents of a Container,” and filed May 1, 2015, which isincorporated herein by this reference in its entirety.

FIELD OF THE DISCLOSURE

This disclosure relates generally to containers of liquid and, moreparticularly, to apparatus for removing liquid contents of a container.

BACKGROUND

Healthcare diagnostics laboratories use diagnostic instruments, such asautomated diagnostic analyzers, for testing and analyzing samples. Knownautomated diagnostic analyzers use various solutions or liquids such asreagents, wash solutions, triggers, diluents, etc. to perform thediagnostic analysis procedures. These liquids are commonly usedthroughout the analysis procedures and, therefore, the analyzerstypically have one or more onboard containers or tanks that hold theliquids. To refill the onboard tanks, smaller bottles or containers ofthe solution or liquid are fluidly coupled to the tanks via screw capswith dip tube assemblies. The liquid contents are then pumped from thecontainers, via the dip tubes assemblies, to the respective onboardtanks. However, this process of installing and uninstalling screw capsand inserting and removing dip tube assemblies into/from bulk solutioncontainers is messy and tedious. Also, some automated diagnosticanalyzers include multiple onboard tanks for storing different liquids.Thus, there may be multiple dip tube assemblies for the onboard tanks,where each of the dip tube assemblies corresponds to a certain onboardtank. Therefore, it can be imperative to connect the correct dip tube tothe correct container of liquid. Otherwise, the wrong liquid can bemistakenly pumped into the wrong onboard tank, thereby compromising theintegrity of the analysis procedures.

Some known container connection assemblies receive a liquid container inan upside down orientation and include a piercing probe that is insertedinto the container to drain the contents. However, the piercing probesare exposed and can be dangerous to operators who are constantlyinserting containers into the connection assemblies. Further, theseconnection assemblies can mistakenly receive the wrong containers havingthe wrong liquid and, thus, they also ultimately suffer from the abovedrawbacks.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 is a perspective view of an example container inserted into anexample cradle for draining the contents of the container andconstructed in accordance with the teachings of this disclosure.

FIGS. 2A, 2B and 2C illustrate example caps having example key rings formating with the example cradle of FIG. 1, which enable the examplecontainer of FIG. 1 to be inserted into the example cradle and drained.

FIG. 3A is a perspective view of one of the example caps of FIGS. 2A-2Cshown without the example key ring.

FIG. 3B is a cross-sectional view of the example cap of FIG. 3A takenalong line C-C of FIG. 3A.

FIG. 4 is a partially cross-sectioned view of the example cradle of FIG.1 without the example container.

FIG. 5 is a perspective view of an example probe mount that may beimplemented with the example cradle of FIG. 1.

FIG. 6A is a top perspective view of an example sliding lock that may beimplemented with the example cradle of FIG. 1.

FIG. 6B is a bottom perspective view of the example sliding lock of FIG.6A.

FIG. 7A is a top perspective view of an example trigger that may beimplemented with the example cradle of FIG. 1.

FIG. 7B is a bottom perspective view of the example trigger of FIG. 7A.

FIG. 8 is a cross-sectional view of the example container and theexample cradle of FIG. 1 taken along line A-A of FIG. 1, where theexample container is in a first position in which the example containeris not fully inserted into the example cradle. The example cap of FIG.2C is employed on the example container and is engaging the examplesliding lock of FIGS. 6A and 6B.

FIG. 9 is another cross-sectional view of the example container and theexample cradle of FIG. 1 taken along line A-A of FIG. 1, where theexample container is in a second position in which the example containeris partially inserted into the example cradle. The example container ispushed down into the example cradle and the example sliding lock is slidinto the example cradle.

FIG. 10 is a cross-sectional view of the example cradle and the examplecontainer of FIG. 1 taken along line B-B of FIG. 1, where the examplecontainer is in a third position in which the example container is fullyinserted into the example cradle and where the contents of the examplecontainer may be drained.

FIG. 11 is a bottom perspective view of the example cradle of FIG. 1illustrating an example latch for securing the example container in theexample cradle.

FIG. 12 is an enlarged view of the example latch of FIG. 11.

FIG. 13 is a perspective view of the example cradle of FIG. 1illustrating an example light disposed within a release button.

FIGS. 14A-14C illustrate an example sequence of removing an examplecontainer from an example cradle in an example drawer of an automateddiagnostic analyzer having multiple ones of the example cradle ofFIG. 1. FIG. 14A illustrates an example button of one of the examplecradles being illuminated. FIG. 14B illustrates the example releasebutton of FIG. 14A being depressed to release the correspondingcontainer. FIG. 14C illustrates the example container of FIG. 14B beingremoved from the example cradle.

FIG. 15 is a block diagram of an example bulk solution system employingthe example cradle of FIG. 1.

FIG. 16 is a flowchart illustrating an example method of inserting acontainer into a cradle to drain the container, which may be implementedusing the example cradle of FIG. 1 and/or the example bulk solutionsystem of FIG. 15.

FIG. 17 is a diagram of a processor platform for use with the examplesdisclosed herein.

Certain examples are shown in the above-identified figures and describedin detail below. In describing these examples, like or identicalreference numbers are used to identify the same or similar elements. Thefigures are not necessarily to scale and certain features and certainviews of the figures may be shown exaggerated in scale or in schematicfor clarity and/or conciseness. Additionally, several examples have beendescribed throughout this specification. Any features from any examplemay be included with, a replacement for, or otherwise combined withother features from other examples.

DETAILED DESCRIPTION

Automated diagnostic instruments or analyzers typically have one or moreonboard tanks for storing (e.g., housing) bulk solutions or liquids(e.g., diluents, triggers, wash liquids, etc.) that are used duringdiagnostic analysis procedures. The tanks are often located within achassis or body of the automated analyzers. To refill or replenish theonboard tanks, individual bottles or containers of bulk liquids arefluidly connected to the onboard tanks and the contents thereof arepumped into the onboard tanks. The containers are equipped with screwcaps and dip tube assemblies are connected to the containers. However,removing the caps from the bulk liquid/solution containers, installingscrew caps and changing dip tube assemblies is messy and cumbersome.Additionally, the dip tube assemblies are often not capable ofaspirating all of the contents of the containers. Thus, when changing abulk solution container, a small amount of liquid solution is oftendiscarded, which, over time, can result in wasted solutions andincreased costs. Further, some diagnostic analyzers have multipleonboard tanks. Therefore, there are multiple fluid lines coupling toeach of the onboard tanks. As such, it is imperative that the correctrefill container is coupled to the correct fluid line. Otherwise, thewrong liquid may be inadvertently supplied to the wrong onboard tank,thereby compromising the integrity of the diagnostic tests.

Disclosed herein are example cradle apparatus for receiving containersof solution or liquid and draining or pumping the liquid therein toanother location (e.g., an onboard tank of a diagnostic analyzer). Theexample cradles have a unique sliding lock that allows only containershaving matching key caps to be inserted into the cradle and drained.Therefore, unlike the dip tube assemblies describe above, the examplecradles may only receive the correct or desired containers having theappropriate liquid therein, thereby reducing the chance of connectingthe wrong container to the wrong fluid line. In some examples, multipleones of the example cradles may be implemented, and each may be fluidlycoupled to a corresponding tank. Each of the cradles may have adifferent key slot in the corresponding sliding lock, so that onlycontainers with the matching key ring can be plugged into the cradlesand emptied.

In some examples disclosed herein, a bulk liquid/solution container isinserted into a corresponding cradle upside down and, once inserted, apiercing probe punctures a cap on the container. The probe is fluidlyconnected to a barb on the bottom of the cradle, where a hose or tubemay be connected to fluidly couple the probe to another location, suchas an onboard storage tank. The cap has a septum and a specific keyring. The cap may be threadably coupled to the container. When thecontainer is inserted upside down into the cradle, the cap engages asliding lock that is disposed within a housing of the cradle. Thesliding lock is located above a tip of the probe and is locked in placeby one or more lockouts. If the cap has the correct key ring, the keyring fits into a key slot in the sliding lock, which engages a triggerthat releases the lockouts and enables the sliding lock to move. Morespecifically, as the container is pushed down into the cradle, the keyring pushes the trigger downward, and beveled edges of the trigger slideagainst the lockouts and force the lock-out sliders outward. As thesliding lock moves downward, the probe, which is stationary, pierces theseptum and extends into the container (e.g., to make a fluid connectionin a system). The contents of the container can be drained or emptiedthrough the probe. In some examples, the cradle includes a second probethat provides a vent (e.g., positive pressure) as the liquid is drainedto prevent a vacuum from forming in the container.

In some examples, once the container is fully inserted into the cradle,a latch secures the container in position. The latch engages a lip onthe cap after the cap has been pushed past the latch. To release thelatch, an operator may push or depress a release button (such as forexample, a release actuator, an eject button, and/or any other suitablerelease mechanism) that causes the latch to release the cap of thecontainer. One or more springs may be disposed in the housing of thecradle to bias the sliding lock upwards. Therefore, when the latch isreleased, the container may be ejected from the housing of the cradle.Thus, the example cradles provide a simpler way to fluidly connect anddisconnect a container to a fluid system.

If a container not having the correct cap (e.g., the correct key ring)is inserted into the cradle, the cap cannot engage the trigger torelease the lockouts. As a result, the lockouts prevent the sliding lockfrom moving and, thus, prevent the container from being pierced by theprobe and drained. In some examples, the cradle includes a sensor (suchas for example, an integral sensor, a capacitive sensor, and/or anyother suitable sensor) for detecting a level of liquid within thecontainer. In some examples, the cradle includes a sensor for detectingwhen the latch is fully engaged (i.e., when the container is fullyinserted). In some examples, the cradle may include one or more lightsor other indicators to indicate different states of the cradle. Forexample, when the container is pushed all the way in and the latch isengaged, a light (e.g., a green light) may illuminate the release button(e.g., which may be transparent or semi-transparent). If the containeris not fully inserted, another light (e.g., a yellow light) mayilluminate the release button. In some examples, when the container isempty or low on liquid, another light (e.g., a red light) may illuminatethe release button.

The example cradles disclosed herein are described in connection withbulk solution or liquid for use in an automated diagnostic analyzer(e.g., an immunoassay (IA) analyzer or a clinical chemistry (CC)analyzer). However, the example cradles may be used in any applicationwhere liquid is to transferred from a container to another location.

An example apparatus disclosed herein includes a housing having a bottomwall, a side wall and an open top. The housing is to receive a containerhaving liquid to be used in an automated diagnostic analyzer. Theexample apparatus includes a probe extending upward from the bottom walltoward the open top. The probe is to drain the liquid from the containerwhen the probe is inserted into the container. The example apparatusalso includes a sliding lock slidably disposed within the housing. Thesliding lock includes an engagement surface, an opening in theengagement surface to receive the probe therethrough when the slidinglock is moved from a first position in which the engagement surface isabove a tip of the probe to a second position in which the engagementsurface is below the tip of the probe, and a key slot in the engagementsurface. The example apparatus includes a lockout located below theengagement surface of the sliding lock releaseably coupled to thesliding lock. The lockout is movable between a locked position in whichthe sliding lock is prevented from moving in the housing and an unlockedposition in which the sliding lock is movable in the housing. The keyslot is to receive a key of the container that is inserted into thehousing to move the lockout from the locked position to the unlockedposition.

In some examples, the apparatus includes a trigger that is disposedbelow the engagement surface of the sliding lock. The trigger isengageable with the key to move the trigger toward the bottom wall ofthe cradle to move the lockout to the unlocked position.

In some examples, the trigger is movable along a first axis and thelockout is movable along a second axis that is perpendicular to thefirst axis. In some such examples, the trigger has a beveled surfacethat is to engage the lockout when the trigger moves toward the bottomwall of the housing to move the lockout along the second axis.

In some examples, the key slot is a ring-shaped slot. In some suchexamples, the key is a ring-shaped protrusion that matches thering-shaped slot.

In some examples, the apparatus includes a resilient member to bias thesliding lock away from the bottom wall of the housing. In some examples,the apparatus includes a latch to engage a rim on the container toreleaseably secure the container in the housing when the container isinserted into the housing. In some such examples, the apparatus includesa release actuator to release the latch. The release actuator has alight that is to illuminate when the container is fully inserted intothe housing.

In some examples, the housing is to receive the container in anupside-down orientation. In some examples, the apparatus includes a barbdisposed on an outer surface of the bottom wall to fluidly couple aninner passage of the probe to a tube coupled to the barb.

Another example apparatus disclosed herein includes a housing having abottom wall, a side wall and an open top. The housing is to receive acontainer having liquid to be used in an automated diagnostic analyzer.The example apparatus includes a probe extending upward from the bottomwall toward the open top. The probe is to drain the liquid from thecontainer when the probe is inserted into the container. The exampleapparatus also includes a sliding lock slidably disposed within thehousing. The sliding lock includes an engagement surface, an opening inthe engagement surface to receive the probe therethrough when thesliding lock is moved from a first position in which the engagementsurface is above a tip of the probe to a second position in which theengagement surface is below the tip of the probe, and a key slot in theengagement surface. The example apparatus includes a lockout releaseablycoupled to the sliding lock to prevent movement of the sliding lock whenthe lockout is in a locked position. The example apparatus also includesa trigger disposed below the engagement surface of the sliding lock. Thetrigger is engageable with a key of the container inserted into the keyslot to move the trigger toward the bottom wall of the housing to movethe lockout to an unlocked position in which the sliding lock is movablein the housing.

In some examples, the sliding lock and the trigger are moveable alongthe same axis. In some examples, the trigger includes a second openingto receive the probe therethrough when the trigger is moved toward thebottom wall of the housing. In some such examples, the second opening ofthe trigger is concentric with and outside of the first opening of thesliding lock.

In some examples, the apparatus includes a first spring to bias thetrigger away from the bottom wall of the housing. In some such examples,the apparatus includes a second spring to bias the sliding lock awayfrom the bottom wall of the housing.

In some examples, the trigger is movable along a first axis and thelockout is movable along a second axis, the second axis perpendicular tothe first axis. In some examples, the trigger includes a beveled surfacethat is to engage the lockout when the trigger is activated to move thelockout in a direction that is perpendicular to the movement of thetrigger.

Another example apparatus disclosed herein includes a housing to receivea container having liquid to be used in an automated diagnosticanalyzer. The housing has a bottom wall, a side wall and an open top.The example apparatus includes a probe extending upward from the bottomwall toward the open top. The probe is to drain the liquid from thecontainer when the probe is inserted into the container. The exampleapparatus also includes a sliding lock slidably disposed within thehousing. The sliding lock includes an engagement surface disposed abovethe probe, an opening in the engagement surface to receive the probetherethrough when the sliding lock is moved toward the bottom wall ofthe housing, and a key slot. The sliding lock is operable between alocked state in which movement of the sliding lock is prevented and anunlocked state in which the sliding lock is movable. The sliding lock isswitched to the unlocked state when a cap of the container includes akey corresponding to the key slot engages the key slot.

An example method is disclosed herein that includes inserting acontainer with a cap having a key ring into a cradle. The cradleincludes a housing, a probe disposed in the housing, a sliding lockslidably disposed in the housing, the sliding lock having (1) anengagement surface, (2) an opening in the engagement surface to receivethe probe therethrough when the sliding lock is moved from a firstposition in which the engagement surface is above a tip of the probe toa second position in which the engagement surface is below the tip ofthe probe, and (3) a key slot in the engagement surface, and a lockoutlocated below the engagement surface of the sliding lock releaseablycoupled to the sliding lock. The example method includes moving thecontainer into the cradle. If the key ring matches the key slot, thelockout is moved between a locked position in which the sliding lockprevented from moving in the housing and an unlocked position in whichthe sliding lock is movable in the housing to the second position. Theexample method also includes coupling the container in the cradle anddraining the contents of the container via the probe.

In some examples, the container is inverted when the container isinserted into the cradle. In some examples, the cradle includes a latchthat is movable between a non-engaged position in which the container ismoveable out of the cradle and an engaged position in which thecontainer is coupled in the cradle. In some such examples, the methodincludes determining, via a latch position sensor, whether the latch isin the non-engaged position or the engaged position. In some suchexamples, the method also includes determining, via a liquid levelsensor, a level of liquid in the container. In some such examples, themethod includes actuating a first indicator when the latch is determinedto be in the engaged position. In some such examples, the method alsoincludes actuating a second indicator when the level of liquid in thecontainer is determined to be below a threshold. In some examples, thefirst indicator s a first color light and the second indicator is asecond color light different than the first color light. In someexamples, the first indicator and the second indicator are disposedwithin a release button of the cradle.

FIG. 1 illustrates an example bulk solution system 100 in which anexample cradle 102 is implemented to receive a bottle or container 104and drain the liquid contents thereof. The contents may be, for example,a reagent, a wash solution, a trigger, a diluent and/or any othersolution or liquid for use in an automated diagnostic analyzer. Theexample container 104 may be any volume desired (e.g., 1 liter). In theillustrated example, the cradle 102 includes a body or housing 105having a bottom wall 106 and a side wall 108 that define an opening(e.g., an open top) to receive a top of the container 104 (as disclosedin further detail herein). When the container 104 is fully inserted intothe cradle 102, the contents of the container 104 can be drained orremoved via one or more openings (e.g., through-holes, apertures) in thebottom wall 106 (disclosed in further detail herein). In the illustratedexample, the cradle 102 includes a container holder 110 (e.g., amolding) that defines an opening 112 that is shaped to receive thecontainer 104 and support the container 104 in an upside down orinverted orientation. In the illustrated example, the container 104 hasa substantially rectangular cross-section with curved edges. However, inother examples, the container 104 may have a circular shapedcross-section or any other shaped cross-section. In the illustratedexample, the cradle 102 has a mounting plate 114 with one or more holes116 that may be used to mount the cradle 102 to another structure (e.g.,to an automated diagnostic analyzer, to a drawer of an analyzer, etc.).

In the illustrated example of FIG. 1, the cradle 102 includes a latch118 and a release button 120 (e.g., an eject button, a releaseactuator). When the container 102 is fully inserted into the cradle 102,the latch 118 secures the container 104 to the cradle 102 to prevent thecontainer 104 from being removed (e.g., inadvertently) from the cradle102. To release the container 104, the release button 120 may bedepressed. The release button 120 engages the latch 118 and therebyreleases the latch 118 from the container 104. The release button 120 isdisposed within a release button housing 122 along a side of thecontainer holder 110. In the illustrated example, the cradle 120includes a circuit board 124 (e.g., a processor, a printable circuitboard (PCB), a microchip, etc.), a latch position sensor 126 (e.g., anencoder, an optical sensor) and a liquid level sensor 128 (e.g., anintegral sensor, a capacitive sensor), which are disclosed in furtherdetail herein.

In the illustrated example, the cradle 102 only accepts containershaving a cap or top with a particular key ring that matches a key slotin the cradle 102 (disclosed in further detail herein). FIGS. 2A, 2B and2C illustrate example caps 200 that may be used with the container 104(FIG. 1). Each of the caps 200 has a key ring 202 that matches a keyslot in a corresponding cradle. In the illustrated examples, the keyrings 200 are in the shape of circles that extend from the caps 200. Thekey ring 202 of the cap 200 in FIG. 2A has relatively small diametercompared to the diameters of the key rings 202 of the caps 200 in FIGS.2B and 2C. The key ring 202 of the cap 200 in FIG. 2C has the largestdiameter, and the key ring 202 of the cap 200 in FIG. 2B has a diameterhaving a dimension between the key rings 202 of the caps 200 in FIGS. 2Aand 2C. The different caps 200 of FIGS. 2A-2C may correspond todifferent containers having different liquids. Each of the caps 200 mayinteract with respective cradles having a matching key slot. Therefore,if one of the caps 200 is inserted into the wrong cradle, the key ring202 may not have the correct diameter key to be received by the cradleand drained. In the illustrated examples, three different sized keyrings 202 are illustrated, where each of the key rings 202 is to be usedwith a particular type of container of liquid. However, it is to beunderstood that many more caps having different diameter key rings couldbe implemented. Additionally or alternatively, other caps havingdifferent shaped key rings may also be implemented (e.g., square,rectangular, etc.).

FIG. 3A illustrates a perspective view of one of the caps 200, and FIG.3B illustrates a cross-sectional view of the cap 200 taken along lineC-C of FIG. 3A. In the illustrated example of FIGS. 3A and 3B, the keyring 200 (FIGS. 2A-2C) has been removed for clarity. The cap 200 has alid or surface 300 with an opening 302 (e.g., an aperture, a hole, achannel) therethrough. A side wall 304 with internal threads 306 extendsfrom one side of the lid 300, and an annular lip or rim 308 extends fromthe other side of the lid 300. The cap 200 may be screwed onto acontainer (e.g., the container 104 of FIG. 1) via the threads 306. Inthe illustrated example, the cap 200 includes a septum 310 that isdisposed within the opening 302 and is held in place by a snap ring 312.The septum 310 may be made of any suitable material, such as silicon orrubber. The snap ring 312 is wedged (e.g., via force fit, via a tab)between an inside of the rim 308 and the septum 310. In the examplesillustrated in FIGS. 2A-2C, the rim is illustrated as a plurality ofindividual extensions. In other examples, such as the exampleillustrated in FIGS. 3A and 3B, the rim is a continuous wall extendingfrom the lid 300.

In the illustrated example, the cap 200 has a wall or flange 314extending outward from the side wall 304. The flange 314 issubstantially parallel to the lid 300. An outer wall 316 extends upwardfrom the flange 314 in a direction that is parallel to the side wall304. The outer wall 316 has a plurality of ribs 318 that allow a user togrip the cap 200 (e.g., when tightening or loosening the cap 200 on acontainer). A lower side wall 320 extends downward from the flange 314and has a plurality of ratchet groves 322, which enable the cap 200 tobe ratcheted tightly onto a container and prevent the cap 200 fromloosening from container. The cap 200 may be constructed of any suitablematerial such as, for example, polypropylene.

FIG. 4 illustrates a partially cross-sectioned view of the examplecradle 102. The container 104 has been removed for clarity. To drain thecontents of a container (e.g., the container 104 of FIG. 1), the cradle102 has a piercing drain probe 400 (e.g., a needle) that may puncture acap and/or a septum on a cap (e.g., the cap 200 of FIG. 3A) and beinserted into a container. The drain probe 400 is coupled to a probemount 402 (e.g., an insert molded probe assembly) that extends throughan opening 404 in the bottom wall 106 of the housing 105. The drainprobe 400 extends or projects upward and away from the bottom wall 106within an opening 406 defined by the bottom wall 106 and the side wall108. In the illustrated example, the cradle 102 includes a vent probe408 that is disposed adjacent the drain probe 400. The vent probe 408 isto vent the inside of a container to prevent a vacuum from forminginside of the container while the contents are drained. The vent probe408 is coupled to the probe mount 402. The probe mount 402 includespassages that couple the probes 400, 408 to first and second barbs 410,412 (e.g., nipples, fittings, adaptors, barbed connectors, etc.),respectively, on an outside of the bottom wall 106. Hoses or tubes maybe coupled to the first and second barbs 410, 412 to fluidly couple thedrain probe 400 and/or the vent probe 408 to a desired location (e.g.,to an onboard tank). The example probe mount 402 is illustrated in FIG.5, which illustrates the drain probe 400, the vent probe 408, and thefirst and second barbs 410, 412.

Referring to FIG. 4, to prevent unintended containers from beinginserted into the housing 105 and pierced and drained, the examplecradle 102 includes a sliding lock 414 that is slidably disposed withinthe opening 406 of the housing 105. FIG. 6A illustrates a topperspective view of the sliding lock 414 and FIG. 6B illustrates abottom perspective view of the sliding lock 414, which are numbered inaccordance with the disclosure herein. The sliding lock 414 has anengagement surface 416 that is to receive a cap or top of a container(e.g., contacted by a cap or top of a container). The engagement surface416 has an opening 418 to receive the probes 400, 408 when the slidinglock 414 is moved downward or toward the bottom wall 106 (e.g., from afirst position to a second position). The sliding lock 414 is movablealong a first axis 419 (e.g., a longitudinal axis of the housing 105).When the sliding lock 414 is moved downward (e.g., when a containerhaving a matching key ring is inserted), the probes 400, 408 extendthrough the opening 418 to pierce a cap and/or septum of a container. Inthe illustrated example of FIG. 4, the sliding lock 414 is a first orunengaged position where the probes 400, 408 are disposed below theengagement surface 416. As such an operator cannot accidently pokehimself/herself. The sliding lock 414 is movable from the first positionto a second position in which the engagement surface 416 is below thetip of the probes 400, 408 (as disclosed in further detail herein).

In the illustrated example, the sliding lock 414 has an outer wall 420that is in the shape of a cylinder or sleeve. The outer wall 420 matchesthe shape of the opening 406 as defined by the side wall 106 of thehousing 105. However, in other examples the outer wall 420 of thesliding lock 414 may be shaped differently. For example, the outer wall420 may be substantially a square or triangular shape.

To prevent the sliding lock 414 from being pushed down towards thebottom wall 106 by an undesired container (e.g., a container with thewrong liquid), the cradle 102 includes a first lockout 422 (e.g., alocking button, a lockout slider) and a second lockout 424 (FIGS. 8 and9), which are disposed in the side wall 108 of the housing 105 andextend into the outer wall 420 of the sliding lock 414. The first andsecond lockouts 422, 424 prevent the sliding lock 414 from moving towardthe bottom wall 106, which would thereby enable the probes 400, 408 toextend through the sliding lock 414 and pierce a cap and/or a septum ofa container. The first and second lockouts 422, 424 are movable betweena locked position (as illustrated in FIGS. 4 and 8) and an unlockedposition (as illustrated in FIG. 9). The first and second lockouts 422,424 are disposed within respective openings 426, 428 (seen more clearlyin FIGS. 8 and 9) in the side wall 108. The first and second lockouts422, 424 are biased via respective first and second springs 430, 432(seen more clearly in FIGS. 8 and 9) toward a center of the cradle 102along a second axis 433, which is perpendicular to the first axis 419along which the sliding lock 416 moves. Retaining caps 434, 436 (e.g.,retaining buttons) are removably coupled to the respective openings 426,428 (e.g., to enable access to the first and second lockouts 422, 424and the first and second springs 430, 432). In the locked position, thefirst and second lockouts 422, 424 extend into (e.g., are inserted into)respective first and second notches 600, 602 (FIGS. 6A and 6B) in theouter wall 420 of the sliding lock 414. As a result, the sliding lock414 is prevented from moving upward or downward and, thus, the probes400, 408 cannot be exposed through the opening 418.

In the illustrated example of FIG. 4, the first and second lockouts 422,424 are located opposite of each other on the side wall 108. However, inother examples, the first and second lockouts 422, 424 are disposed inother locations (e.g., closer to each other) and/or at different lengthsor heights along the side wall 108. In some examples, only one lockoutis implemented. In other examples, more than two lockouts areimplemented.

To release the first and second lockouts 422, 424, the cradle 102includes a trigger 438 that is disposed between the sliding lock 414 andthe bottom wall 106 (e.g., beneath the engagement surface 416 of thesliding lock 414). FIG. 7A illustrates a top perspective view of thetrigger 438 and FIG. 7B illustrates a bottom perspective view of thetrigger 438, which are numbered in accordance with the disclosureherein. The trigger 438 has an engagement surface 440 that is parallelto the engagement surface 416 of the sliding lock 414. The engagementsurface 440 of the trigger 438 has an opening 442 that is concentricwith the opening 418 of the sliding lock 414. As illustrated in FIG. 4,the trigger 438 is movable along the first axis 419. As illustrated inFIGS. 7A and 7B, the trigger 438 has a first tab 700 with a beveled orangled surface and a second tab 702 with a beveled or angled surface. Inthe illustrated example, the first and second tabs 700, 702 extendoutward from the engagement surface 440. As illustrated in FIGS. 6A and6B, the sliding lock 414 has a first slot 604 and a second slot 606 thatreceive the respective first and second tabs 700, 702 of the trigger438. The first and second slots 604, 604 intersect the first and secondnotches 600, 602, respectively. Therefore, when the trigger 438 is movedtoward the bottom wall 106, the first and second tabs 700, 702 engagethe respective first and second lockouts 422, 424 and force the firstand second lockouts 422, 424 outward (e.g., along the second axis 433)such that the first and second lockouts 422, 424 are disengaged from thefirst and second notches 600, 602 in the outer wall 420 of the slidinglock 414. As a result, the sliding lock 414 is able to be moved downwardtoward the bottom wall 106.

To move the trigger 438 (which is disposed beneath the engagementsurface 416 of the sliding lock 414) downward to disengage the first andsecond lockouts 422, 424, the sliding lock 414 has a key slot 446 in theengagement surface 416. The key slot 446 is an opening that has a shapecorresponding to a particularly key ring of a cap. When a cap having amatching or corresponding key ring is inserted into the cradle 102, thekey ring fits within the key slot 446 and engages the trigger 438 (e.g.,the engagement surface 440 of the trigger 438) to move the trigger 438toward the bottom wall 106 and, thus, release the first and secondlockouts 422, 424 from the sliding lock 414. Once the first and secondlockouts 422, 424 are disengaged, the sliding lock 414 is free to bepushed toward the bottom wall 106. As the sliding lock 414 is moveddownward, the probes 400, 408 extend through the opening 418 and engagethe cap of the container. In the illustrated example, the key slot 446is a ring-shaped slot. However, in other examples, the key slot 446 maybe any other shape (e.g., a triangle, a square, a star, etc.) and/orother size that corresponds to a particular key shape on a cap of acontainer.

As illustrated in FIGS. 6A and 6B, the key slot 446 divides theengagement surface 416 into an inner surface 608 and an outer surface610. The inner and outer surface 608, 610 are coupled together via asupport bar 612. The support bar 612 includes notches 614 at theintersection of the key slot 416 to accommodate a key ring when the keyring is inserted into the key slot 416, thereby enabling the key ring toengage the trigger 438. As illustrated in FIGS. 7A and 7B, the trigger438 has a slot 704 in the engagement surface 440 to receive the supportbar 612 when the trigger 438 is disposed below the sliding lock 414(e.g., as illustrated in the position in FIG. 4). In the illustratedexample of FIG. 6A, the engagement surface 416 of the sliding lock 414includes a recess 613 to receive the rim 308 of the cap 200 (FIG. 3).

In the illustrated example of FIG. 4, the cradle 102 includes a firstspring 448 (e.g., a resilient member, a return spring, and/or any othersuitable biasing device) that is disposed between the bottom wall 106and the sliding lock 414 to bias the sliding lock 414 upward and awayfrom the bottom wall 106. The first spring 448 applies an upward forcedto eject the bottle 104 from the cradle 102. In the illustrated example,the cradle 102 includes a second spring 450 that is disposed between thebottom wall 106 and the trigger 440 to bias the trigger 400 upward andaway from the bottom wall 106. In other examples, other mechanisms maybe used to bias the sliding lock 414 and/or the trigger 438.

To secure a container to the cradle 102 once a container is insertedinto the cradle 102 and moved down so that the probes 400, 408 aredisposed within the container, the latch 118 (e.g., a sliding latch, alever, a trigger) is provided to engage a lip or rim on a cap of acontainer to prevent the container from being forced upward (e.g., viathe first spring 448 and/or the second spring 450). The latch 118 movesalong a third axis 453 (FIGS. 4 and 10) that is perpendicular to thefirst axis 419 along which the sliding lock 414 moves. The latch 118 hasa beveled edge 454. When the release button 120 is pushed downward, abeveled edge 456 of the release button 120 engages the beveled edge 454of the latch 118 and moves the latch 118 outward along the third axis453 (e.g., away from a center of the cradle 102). As a result, the latch118 releases the rim or lip of the cap and the container is free to beremoved from the cradle 102 (e.g., via the force provided by the firstand second springs 448, 450).

FIG. 8 illustrates a cross-sectional view of the cradle 102 and thecontainer 104 of FIG. 1 (taken along line A-A of FIG. 1) when thecontainer 104 is a first position and as the container 104 is insertedinto the cradle 102. In the illustrated example, the container 104 isinverted upside down and placed into the opening 112 defined by thecontainer holder 110. In the illustrated example, the cap 200 of FIG. 2Chas been threaded onto an opening 800 (e.g., a mouth) of the container104 (e.g., via the threads 306). As illustrated in the example of FIG.8, the first and second lockouts 422, 424, which are disposed within therespective first and second openings 426, 428 of the wall 108, arebiased inward toward a center of the cradle 102 via the respective firstand second springs 430, 432. The first and second lockouts 422, 424 aremovable along the second axis 433, which is perpendicular to the firstaxis 419 along which the sliding lock 414 moves. In the illustratedexample, the first and second lockouts 422, 424 are in a locked orengaged position in which they are inserted into the respective firstand second notches 600, 602 in the outer wall 420 of the sliding lock414. As a result, the sliding lock 414 is prevented from moving upwardor downward in the housing 105.

In the illustrated example, the cap 200 is the matching cap that enablesthe container 104 to be inserted into the cradle 102 to move the slidinglock 414. In particular, the key ring 202 of the cap 200 matches theshape of the corresponding key slot 446 in the engagement surface 416 ofthe sliding lock 414. Therefore, when the container 104 is pushed downinto the cradle 102, the key ring 202 extends through the key slot 446and engages the engagement surface 440 of the trigger 438. The outerwall 316 of the cap 200 is received by the outer wall 420 of the slidinglock 414 and aligns the cap 200 within the sliding lock 414.

FIG. 9 illustrates a cross-sectional view of the cradle 102 and thecontainer 104 (also taken along line A-A of FIG. 1) when the container104 is in a second position in which the container 104 is partiallyinserted into the cradle 102 (e.g., when the container 104 is pushedfurther down into the cradle 102 than the position of FIG. 8). Asillustrated, the lid 300 of the cap 200 engages the engagement surface416 of the sliding lock 414, and the key ring 202 is inserted throughthe key slot 446 and engages the engagement surface 440 of the trigger438 to move the trigger 438 downward toward the bottom wall 106. Thebeveled surfaces of the first and second tabs 700, 702 of the trigger438 engage the first and second lockouts 422, 424, respectively, andpush the first and second lockouts 422, 424 outward (e.g., along thesecond axis 433) away from the first and second notches 600, 602 in theouter wall 420 of the sliding lock 414. As a result, the sliding lock414 is free to move (e.g., with the trigger 438) downward toward thebottom wall 106 (e.g., along the first axis 419). As the container 104and sliding lock 414 move downward toward the bottom wall 106, theprobes 400, 408 (see FIG. 4) extend through the opening 418 in thesliding lock 414 and pierce the septum 310 in the cap 200 and extendinto the opening 800 of the container 104. In some examples, a pump isactivated that creates a suction in the drain probe 400 to activelyremove the liquid contents of the container 104. In other examples, thecontents of the container 104 may be drained via gravity (e.g., withoutthe assistance of a pump).

FIG. 10 illustrates a cross-sectional view of the cradle 102 and thecontainer 104 taken along line B-B of FIG. 1. In the illustratedexample, the container 104 is in a third position in which the containeris fully inserted into the cradle 102. Additionally, the sliding lock414 is in the engaged or second position. Once the container 104 isfully inserted, the latch 118 extends inward toward a center of thecradle 102 and over the flange 314 of the cap 200, thereby preventingthe container 104 from being release from the cradle 102 (e.g., via theforce of the first and second springs 448, 450 (FIG. 4)). The latch 118is movable along the third axis 453, which is perpendicular to the firstaxis 419 along which the sliding lock 414 moves. To bias the latch 118inward toward a center the cradle 102, a spring 1000 is coupled betweenthe latch 118 and the side wall 108. In the illustrated example, thedrain probe 400 and the vent probe 408 extend through the opening 418 inthe sliding lock 414, through the opening 302 of the cap 200 (and theseptum 310), and into the opening 800 of the container 104. The contentsof the container 104 can then be drained through the drain probe 400.Positive pressure air may be provided through the vent probe 408 toprevent a vacuum from forming inside of the container 104. In theillustrated example, the vent probe 408 is longer or extends furtherthan the drain probe 400. However, in other examples, the probes 400,408 may be equal lengths or heights. In other examples, the probes 400,408 may be longer or shorter and, thus, extend into the container 104further or extend into the container 104 less.

In the illustrated example, the sensor 128 measures the level of liquidin the container 104. The sensor 128 may detect when liquid contents ofthe container 104 are low and/or empty. In the illustrated example, thesensor 128 is a capacitive sensor, which can sense through the wall ofthe housing 105 and through the wall of the container 104 to sense alevel of liquid within the container 104. In other examples, other typesof liquid sensors may be implemented.

When the container 104 is empty, or it is desired to remove thecontainer 104 (such as for example, upon a recall or an expiration ofthe contents of the container 104), the release button 120 may bedepressed or pushed downward. As the release button 120 moves downward,the beveled edge 456 of the release button 120 engages the beveled edge454 of the latch 118 and forces the latch 118 to retract, outward, alongthe third axis 453. In the illustrated example, a spring 1002 isdisposed in the release button channel 122 that biases the releasebutton 120 upwards or away from the latch 118. When the latch 118 ismoved outward or away from the center of the cradle 102, the latch 118clears the flange 314 and the sliding lock 414 is able to move upwardsaway from the bottom wall 106 to eject the container 104 (e.g., via theforce of the first spring 458 (FIG. 4)).

In the illustrated example, and as illustrated in FIGS. 6A and 6B, thesliding lock 414 has a first tab 616 and a second tab 618 (e.g., ears)that project or extend outward from the outer wall 420. When assemblingthe cradle 102, the sliding lock 414 is inserted into the housing 105and the first and second tabs 616, 618 flex inward. Once inserted, thefirst and second tabs 616, 618 project outward into respective first andsecond slots 1004, 1006 in the side wall 108. The first and second tabs616, 616 prevent the sliding lock 414 from being forced (e.g., via thefirst spring 448) upward and out of the housing 105. In some examples, atool is needed to bend the first and second tabs 616, 618 back inwardsto remove the sliding lock 414 from the housing 105. As illustrated inFIG. 10, the cradle 102 has a drain barb 1008 extending from the bottomwall 106. The drain barb 1008 enables liquid to be drained from thebottom of the housing 105 if any excess liquid is spilled into thebottom of the housing 105, for example.

FIG. 11 shows a bottom perspective view of the cradle 102 and FIG. 12shows an enlarged view of the latch 118 as illustrated in FIG. 11. Thecontainer holder 110, the first and second barbs 410, 412, the probemount 402 and the drain barb 1008 are shown in FIG. 11. As illustratedin FIG. 12, the latch 118 has an opening 1200 to receive the bevelededge 456 of the release button 120 as the release button 120 is pusheddownward.

As illustrated in FIGS. 10-12, the latch 118 has a leg 1010 with a notch1012. The leg 1010 is received by the position sensor 126. The sensor126 determines the position of the latch 118 (e.g., based the locationof the notch 1012). When the latch 118 is fully engaged (as in theposition illustrated in FIG. 10), the sensor 126 may determine that thelatch 118 is properly engaged and the container 104 is secure within thecradle 102. Otherwise, the sensor 126 may determine that the latch 118is partially engaged (e.g., when the sliding lock 414 is moved towardthe bottom wall 106) and/or not engaged (e.g., when the release button120 is depressed and the latch 118 is fully retracted, when the sidinglock 414 is in the uppermost position and the latch 118 is engaging theouter wall 420 of the sliding lock 414). In some examples, the positionsensor 126 is an optical sensor. In other examples, other types ofsensors may be implemented. The position sensor 126 and the level sensor128 are communicatively coupled (e.g., via wires or wirelessly) to thecircuit board 124.

In some examples, one or more lights are provided in the release button120 to indicate different states or statuses of the container 104 and/orthe cradle 102. FIG. 13 illustrates the example cradle 102 in which thehousing 105 and the container holder 110 are shown as transparent. Inthe illustrated example, a light 1300 is disposed within the releasebutton 120. The light 1300 may blink or illuminate and/or use differentcolors depending on the state of the container 104 and/or the cradle102. For example, when the container 104 is fully inserted and the latch118 is in the locked position (FIGS. 10-12), the release button 120 maybe illuminated a certain color (e.g., green) by the light 1300. In someexamples, when the container 104 is empty or the liquid level is low(e.g., as detected by the sensor 128), the release button 120 may beilluminated another color (e.g., red) by the light 1300. Additionally oralternatively, different sequences of a blinking light may be used toindicate the different states or status. In some examples, the releasebutton 120 is transparent or semi-transparent. In some examples, thenlight 1300 is a light emitting diode (LED). In some examples, more thanone light is implemented (e.g., multiple LEDs). Some examples mayinclude a display to present human-readable indicia regarding suchstates or status. The light 1300 is communicatively coupled (e.g., via awire or wirelessly) to the circuit board 124.

FIGS. 14A-14C illustrate an example drawer 1400 of an automateddiagnostic analyzer or instrument having multiple ones of the cradle102. The drawer 1400 may be part of a body or chassis of automateddiagnostic analyzer or instrument and may be pulled out to check, add orreplace containers to the cradles 102. Each of the cradles 102 mayconnect to the same or different onboard tanks that are to be filledwith the liquid in the containers 104. In the illustrated example, thecradles 102 are arranged in a 3 by 3 pattern or grid with eight cradles102 (e.g., there is one empty spot). In other examples, the drawer 1300may have more or fewer cradles 102 and/or the cradles 102 may bearranged in different configurations (e.g., a 4 by 4 pattern). Thecradles 102 may be configured to accept the same type of cap ordifferent caps. For example, one or more of the cradles 102 may have asliding lock (e.g., the sliding lock 414 of FIG. 4) that only acceptsthe caps 200 of FIG. 2B, which have medium diameter key rings 202, whileother ones of the cradles 102 may have a sliding lock that only acceptsthe caps 200 of FIG. 2C, which has the largest diameter key ring 202.Thus, the wrong liquid containers cannot be fully inserted into thewrong cradles 102.

In some examples, when the container 104 is empty, the release button120 of the corresponding cradle 102 may illuminate (e.g., via theexample light 1300 as illustrated in FIG. 13). In some examples, therelease button 120 illuminates different colors to indicate differentstates of the operation. For example, the release button 120 mayilluminate a particular color (e.g., red) when the correspondingcontainer 104 is empty or low. In some examples, the release button 120may illuminate another color (e.g., yellow) when the container 104 isnot fully inserted or incorrectly inserted (e.g., in the positionillustrated in FIG. 9).

As illustrated in FIG. 14B, the release button 120 may be depressed torelease the latch (e.g., the latch 118 of FIG. 4) of the correspondingcradle 102 to eject the container 104. As illustrated in FIG. 14C, oncereleased, the container 104 can then be removed from the correspondingcradle 102. Another container (e.g., having the appropriate the matchingcap) can be inserted into the cradle 102 and pushed into the cradle 102to couple the replacement container to the cradle 102.

FIG. 15 is a block diagram of an example bulk solution system 1500 thatmay be used to supply a liquid (e.g., a bulk solution liquid for anautomated diagnostic analyzer) from a first bottle or container toanother bottle or container (e.g., an onboard tank). In the illustratedexample, the bulk solution system 1500 includes the cradle 102 havingthe circuit board or processor 124, the latch position sensor 126, theliquid level sensor 128, and one or more indicator(s) 1502 such as, forexample, a light.

In the illustrated example, the latch position sensor 126 senses ormeasures the position of the latch 118 (FIG. 1). The latch positionsensor 126 may sense if the latch 118 is in one or more positions. Forexample, the latch position sensor 126 may sense if the latch 118 is ina fully engaged position (as illustrated in FIG. 10), a partiallyengaged (e.g., when the sliding lock 414 (FIG. 9) is moved toward thebottom wall 106) and/or not engaged (e.g., when the sliding lock 414 isin the upper position as illustrated in FIG. 8). The latch positionsensor 126 is communicatively coupled to the processor 124. Theprocessor 124 may be used to control the indicator(s) 1502 to indicatethe position of the latch 118 as sensed by the latch position sensor126. The indicator(s) 1502 may correspond to, for example, the light(s)1300 (FIG. 13) that illuminate (e.g., blink or illuminate continuously)different colors depending on the position of the latch 118.

In the illustrated example, the liquid level sensor 128 senses ormeasures the level of liquid of remaining in the container 104 (FIG. 1).The liquid level sensor 128 is communicatively coupled to the processor124. The processor 124 may be used to control the indicator(s) 1502 toindicate when the level of liquid is low as sensed by the liquid levelsensor 128. For example, when the liquid level sensor 128 determines theremaining liquid is below a threshold, the processor 124 may control theindicator(s) 1300 to illuminate (e.g., blink red or yellow).

In the illustrated example, the cradle 102 is communicatively coupled toa control system 1504. The control system 1504 may be a system used tocontrol an automated diagnostic analyzer, for example. The controlsystem 1504 is communicatively coupled to a pump 1506. When a containeris fully and properly inserted into the cradle 102, the processor 124transmits a message to the control system 1504 that the container isready to be drained. The control system 1504 controls the pump 1506 topump the contents of the container 104 (via the drain probe 400) fromthe container 104 to an onboard tank. In other examples, the cradle 102may be communicatively coupled directly to the pump and may control thepump directly.

In the illustrated example, the latch position sensor 126, the liquidlevel sensor 128 and the indicator(s) 1502 are communicatively coupledto the processor 124 (and/or to each other) via communication links1508, and the cradle is communicatively coupled the control system 1504and the pump 1506 via communication links 1510. The communication links1508, 1510 may be any type of wired connection (e.g., a databus, a USBconnection, etc.) or a wireless communication mechanism (e.g., radiofrequency, infrared, etc.) using any past, present or futurecommunication protocol (e.g., Bluetooth, USB 2.0, USB 3.0, etc.).

While an example manner of implementing the bulk solution system 1500 isillustrated in FIG. 15, one or more of the elements, processes and/ordevices illustrated in FIG. 15 may be combined, divided, re-arranged,omitted, eliminated and/or implemented in any other way. Further, theexample processor 124, the example latch position sensor 126, theexample liquid level sensor 128, the example indicator(s) 1502, theexample control system 1504, the example pump 1506 and/or, moregenerally, the example bulk solution system 1500 of FIG. 15 may beimplemented by hardware, software, firmware and/or any combination ofhardware, software and/or firmware. Thus, for example, any of theexample processor 124, the example latch position sensor 126, theexample liquid level sensor 128, the example indicator(s) 1502, theexample control system 1504, the example pump 1506 and/or, moregenerally, the example bulk solution system 1500 could be implemented byone or more analog or digital circuit(s), logic circuits, programmableprocessor(s), application specific integrated circuit(s) (ASIC(s)),programmable logic device(s) (PLD(s)) and/or field programmable logicdevice(s) (FPLD(s)). When reading any of the apparatus or system claimsof this patent to cover a purely software and/or firmwareimplementation, at least one of the example processor 124 and/or theexample control system 1504 is/are hereby expressly defined to include atangible computer readable storage device or storage disk such as amemory, a digital versatile disk (DVD), a compact disk (CD), a Blu-raydisk, etc. storing the software and/or firmware. Further still, theexample bulk solution system 1500 of FIG. 15 may include one or moreelements, processes and/or devices in addition to, or instead of, thoseillustrated in FIG. 15, and/or may include more than one of any or allof the illustrated elements, processes and devices.

A flowchart representative of example method for implementing theexample bulk solution system 1500 is shown in FIG. 16. In this example,the method may be implemented using machine readable instructions thatcomprise a program for execution by a processor such as the processor1712 shown in the example processor platform 1700 discussed below inconnection with FIG. 17. The program may be embodied in software storedon a tangible computer readable storage medium such as a CD-ROM, afloppy disk, a hard drive, a digital versatile disk (DVD), a Blu-raydisk, or a memory associated with the processor 1712, but the entireprogram and/or parts thereof could alternatively be executed by a deviceother than the processor 1712 and/or embodied in firmware or dedicatedhardware. Further, although the example program is described withreference to the flowchart illustrated in FIG. 16, many other methods ofimplementing the example bulk solution system 1500 may alternatively beused. For example, the order of execution of the blocks may be changed,and/or some of the blocks described may be changed, eliminated, orcombined.

As mentioned above, the example method of FIG. 16 may be implementedusing coded instructions (e.g., computer and/or machine readableinstructions) stored on a tangible computer readable storage medium suchas a hard disk drive, a flash memory, a read-only memory (ROM), acompact disk (CD), a digital versatile disk (DVD), a cache, arandom-access memory (RAM) and/or any other storage device or storagedisk in which information is stored for any duration (e.g., for extendedtime periods, permanently, for brief instances, for temporarilybuffering, and/or for caching of the information). As used herein, theterm tangible computer readable storage medium is expressly defined toinclude any type of computer readable storage device and/or storage diskand to exclude propagating signals and to exclude transmission media. Asused herein, “tangible computer readable storage medium” and “tangiblemachine readable storage medium” are used interchangeably. Additionallyor alternatively, the example method of FIG. 16 may be implemented usingcoded instructions (e.g., computer and/or machine readable instructions)stored on a non-transitory computer and/or machine readable medium suchas a hard disk drive, a flash memory, a read-only memory, a compactdisk, a digital versatile disk, a cache, a random-access memory and/orany other storage device or storage disk in which information is storedfor any duration (e.g., for extended time periods, permanently, forbrief instances, for temporarily buffering, and/or for caching of theinformation). As used herein, the term non-transitory computer readablemedium is expressly defined to include any type of computer readablestorage device and/or storage disk and to exclude propagating signalsand to exclude transmission media. As used herein, when the phrase “atleast” is used as the transition term in a preamble of a claim, it isopen-ended in the same manner as the term “comprising” is open ended.

FIG. 16 is a flowchart representative of an example method 1600 ofcoupling a container to a cradle, which may be used for transferringliquid from the container to another container, and which may beimplemented (at least in part) using the example cradle 102 of FIG. 1and/or the bulk solution system 1500 of FIG. 15. In the illustratedexample, the method 1600 includes coupling a cap having a key ring ontoa container (1602). For example, one of the caps 200 (FIG. 2) may bethreadably coupled to the container 104 (FIG. 1). In other examples, thecap 200 may be coupled to the container 104 via other couplingtechniques. In some examples, no cap is used. Instead, the container 104may include a key ring extending from the container 104 (e.g., at ornear the mouth 800).

The example method 1600 includes inverting the container (1604) andinserting the container into a cradle (block 1606). For example, asillustrated in FIGS. 8, 9 and 10, the container 104 is inverted (e.g.,turned upside down) and inserted into the cradle 104. If the cap 200 hasthe correct key ring 202, the key ring 202 extends through the key slot446 to engage the trigger 438. In some examples, the container 104 maybe inserted into or otherwise fluidly coupled to the cradle 102 withoutinversion.

The example method 1600 includes advancing the container into the cradleto expose a drain probe (block 1608). For example, as illustrated inFIGS. 8, 9 and 10, as the container 104 is advanced into the cradle 102,the key ring 202 pushes the trigger 438 to disengage the first andsecond lockouts 422, 424, thereby enabling the sliding lock 414 to movetoward the bottom wall 106. As the container 104 and the sliding lock414 move downward, the drain probe 400 extends through the opening 418of the sliding lock 414 to pierce the cap 200.

The example method 1600 includes determining whether a latch is in afully engaged position (block 1610). If the latch is not in a fullyengaged position, the container is to be advanced further into thecradle (block 1608). If the latch is in the fully engaged position, thenan indicator is activated such as, for example, illuminating a light toindicate that the container is ready to be drained (block 1612). Forexample, as illustrated in FIG. 10, the latch 118 is in a fully engagedposition where the latch 118 extends over the flange 314 on the cap 200to secure the container 104 within the cradle 102. The latch positionsensor 126 determines the position of the latch 118. If the latch 118 isfully engaged, the indicator(s) 1502 (FIG. 15) may be actuated (e.g.,via a command from the processor 124) to indicate the container 104 isproperly inserted into the cradle 102 and ready to be drained. In someexamples, if the latch 118 is not fully engaged, then another indicator1502 (e.g., another color light) may be actuated to indicate thecontainer 104 has not been fully inserted into the cradle 102. In theillustrated example of FIGS. 1-14B the indicator 1502 may correspond tothe light(s) 1300 (FIG. 13), which is disposed within the release button120. However, in other examples, the indicator 1502 may be disposed in adifferent location on or near the cradle 102.

In the illustrated example of FIG. 16, the method 1600 includes drainingthe contents of the container (block 1614). In some examples, thecontents of the container 104 may be drained via gravity. In otherexamples, such as illustrated in FIG. 15, the pump 1506 may be used topump the liquid contents from the container 104. The pump 1506 may becontrolled by the control system 1504 and/or the processor 126 of thecradle 102.

The example method 1600 includes determining if the level of liquid inthe container is low (block 1616). If the level of liquid is not low,then the contents of the container may be drained (block 1614) asdesired. If the level of liquid is low or empty, then an indicator isactuated to indicate the container is low on liquid (block 1618). Forexample the cradle 102 includes the liquid level sensor 128 to sense alevel of liquid remaining in the container 104. If the level of liquidis low, then the indicator 1502 (FIG. 15) may be actuated (e.g., adifferent color light is illuminated than the color used to indicate thelatch 118 is fully engaged). For example, the indicator 1502 may be alight (e.g., the light 1300 (FIG. 13) that blinks red or yellow.

The example method 1600 includes ejecting and removing the containerfrom the cradle (block 1620) by, for example, pushing a release button.For example, as illustrated in FIGS. 14A-14C, the release button 120 ispushed to eject the container 104 from the cradle 102. Another containerhaving a cap with the correct key ring may then be inserted into thecradle 102. In some examples, the motion of inserting the container 104into the cradle 102 and pushing the container 104 down until the latch118 is in the fully engaged position is performed on continuous motion(e.g., by an operator or technician).

The example method 1600 includes determining if the container is to bereplaced (block 1622) with, for example, an additional container havingthe same or different contents. If the container is to be replaced, theexample method 1600 continues with coupling a cap having a key to thenew or replacement container (block 1602), and so forth. If thecontainer is not to be replaced (block 1622), the example method 1600ends (block 1624).

FIG. 17 is a block diagram of an example processor platform 1700 capableof executing instructions to implement the method 1600 of FIG. 16 andexample bulk solution system 1500 of FIG. 15. The processor platform1700 can be, for example, a server, a personal computer, a mobile device(e.g., a cell phone, a smart phone, a tablet such as an iPad™), apersonal digital assistant (PDA), an Internet appliance, a DVD player, aCD player, a digital video recorder, a Blu-ray player, or any other typeof computing device.

The processor platform 1700 of the illustrated example includes aprocessor 1712. The processor 1712 of the illustrated example ishardware. For example, the processor 1712 can be implemented by one ormore integrated circuits, logic circuits, microprocessors or controllersfrom any desired family or manufacturer.

The processor 1712 of the illustrated example includes a local memory1713 (e.g., a cache). The processor 1712 of the illustrated example isin communication with a main memory including a volatile memory 1714 anda non-volatile memory 1716 via a bus 1718. The volatile memory 1714 maybe implemented by Synchronous Dynamic Random Access Memory (SDRAM),Dynamic Random Access Memory (DRAM), RAMBUS Dynamic Random Access Memory(RDRAM) and/or any other type of random access memory device. Thenon-volatile memory 1716 may be implemented by flash memory and/or anyother desired type of memory device. Access to the main memory 1714,1716 is controlled by a memory controller.

The processor platform 1700 of the illustrated example also includes aninterface circuit 1720. The interface circuit 1720 may be implemented byany type of interface standard, such as an Ethernet interface, auniversal serial bus (USB), and/or a PCI express interface.

In the illustrated example, one or more input devices 1722 are connectedto the interface circuit 1720. The input device(s) 1722 permit(s) a userto enter data and commands into the processor 1712. The input device(s)can be implemented by, for example, an audio sensor, a microphone, acamera (still or video), a keyboard, a button, a mouse, a touchscreen, atrack-pad, a trackball, isopoint and/or a voice recognition system.

One or more output devices 1724 are also connected to the interfacecircuit 1720 of the illustrated example. The output devices 1724 can beimplemented, for example, by display devices (e.g., a light emittingdiode (LED), an organic light emitting diode (OLED), a liquid crystaldisplay, a cathode ray tube display (CRT), a touchscreen, a tactileoutput device, a printer and/or speakers). The interface circuit 1720 ofthe illustrated example, thus, typically includes a graphics drivercard, a graphics driver chip or a graphics driver processor.

The interface circuit 1720 of the illustrated example also includes acommunication device such as a transmitter, a receiver, a transceiver, amodem and/or network interface card to facilitate exchange of data withexternal machines (e.g., computing devices of any kind) via a network1726 (e.g., an Ethernet connection, a digital subscriber line (DSL), atelephone line, coaxial cable, a cellular telephone system, etc.).

The processor platform 1700 of the illustrated example also includes oneor more mass storage devices 1728 for storing software and/or data.Examples of such mass storage devices 1728 include floppy disk drives,hard drive disks, compact disk drives, Blu-ray disk drives, RAIDsystems, and digital versatile disk (DVD) drives.

Coded instructions 1732 to implement the method 1600 of FIG. 16 may bestored in the mass storage device 1728, in the volatile memory 1714, inthe non-volatile memory 1716, and/or on a removable tangible computerreadable storage medium such as a CD or DVD.

While the example cradles disclosed herein were described in connectionwith bulk solution liquids for an automated diagnostic analyzer, theexample cradles may be used in any application where a liquid is to bedrain from a bottle, inverted or upright. From the foregoing, it will beappreciated that the above disclosed cradles provide a relatively safermeans for piercing a cap and/or septum on a container and draining theliquid contents therein. The example cradles employ a unique lockingsystem that prevents bottles having the wrong caps from being insertedinto the cradles and drained (e.g., by mistake). Further, the examplecradles include sensors that determine whether a container is fully andproperty inserted into a cradle and/or the level of liquid remainingwithin the container.

Although certain example apparatus and methods, and articles ofmanufacture have been disclosed herein, the scope of coverage of thispatent is not limited thereto. On the contrary, this patent covers allmethods, apparatus and articles of manufacture fairly falling within thescope of the claims of this patent.

What is claimed is:
 1. An apparatus comprising: a housing having abottom wall, a side wall and an open top, the housing to receive acontainer having liquid to be used in an automated diagnostic analyzer;a probe extending upward from the bottom wall toward the open top, theprobe to drain the liquid from the container when the probe is insertedinto the container; a sliding lock slidably disposed within the housing,the sliding lock comprising: an engagement surface; an opening in theengagement surface to receive the probe therethrough when the slidinglock is moved from a first position in which the engagement surface isabove a tip of the probe to a second position in which the engagementsurface is below the tip of the probe; and a key slot in the engagementsurface; and a lockout located below the engagement surface of thesliding lock releaseably coupled to the sliding lock, the lockoutmovable between a locked position in which the sliding lock is preventedfrom moving in the housing and an unlocked position in which the slidinglock is movable in the housing, wherein the key slot is to receive a keyof the container that is inserted into the housing to move the lockoutfrom the locked position to the unlocked position.
 2. The apparatus ofclaim 1 further comprising a trigger disposed below the engagementsurface of the sliding lock, the trigger engageable with the key to movethe trigger toward the bottom wall of the cradle to move the lockout tothe unlocked position.
 3. The apparatus of claim 2, wherein the triggeris movable along a first axis and the lockout is movable along a secondaxis, the second axis perpendicular to the first axis.
 4. The apparatusof claim 3, wherein the trigger comprises a beveled surface that is toengage the lockout when the trigger moves toward the bottom wall of thehousing to move the lockout along the second axis.
 5. The apparatus ofclaim 1, wherein the key slot is a ring-shaped slot.
 6. The apparatus ofclaim 5, wherein the key is a ring-shaped protrusion that matches thering-shaped slot.
 7. The apparatus of claim 1 further comprising aresilient member to bias the sliding lock away from the bottom wall ofthe housing.
 8. The apparatus of claim 1 further comprising a latch toengage a rim on the container to releaseably secure the container in thehousing when the container is inserted into the housing.
 9. Theapparatus of claim 8 further comprising a release actuator to releasethe latch, the release actuator having a light that is to illuminatewhen the container is fully inserted into the housing.
 10. The apparatusof claim 1, wherein the housing is to receive the container in anupside-down orientation.
 11. The apparatus of claim 1 further comprisinga barb disposed on an outer surface of the bottom wall to fluidly couplean inner passage of the probe to a tube coupled to the barb.
 12. Anapparatus comprising: a housing having a bottom wall, a side wall and anopen top, the housing to receive a container having liquid to be used inan automated diagnostic analyzer; a probe extending upward from thebottom wall toward the open top, the probe to drain the liquid from thecontainer when the probe is inserted into the container; a sliding lockslidably disposed within the housing, the sliding lock comprising: anengagement surface; an opening in the engagement surface to receive theprobe therethrough when the sliding lock is moved from a first positionin which the engagement surface is above a tip of the probe to a secondposition in which the engagement surface is below the tip of the probe;and a key slot in the engagement surface; a lockout releaseably coupledto the sliding lock to prevent movement of the sliding lock when thelockout is in a locked position; and a trigger disposed below theengagement surface of the sliding lock, the trigger engageable with akey of the container inserted into the key slot to move the triggertoward the bottom wall of the housing to move the lockout to an unlockedposition in which the sliding lock is movable in the housing.
 13. Theapparatus of claim 12, wherein the sliding lock and the trigger aremoveable along the same axis.
 14. The apparatus of claim 12, wherein thetrigger comprises a second opening to receive the probe therethroughwhen the trigger is moved toward the bottom wall of the housing.
 15. Theapparatus of claim 14, wherein the second opening of the trigger isconcentric with and outside of the first opening of the sliding lock.16. The apparatus of claim 12 further comprising a first spring to biasthe trigger away from the bottom wall of the housing.
 17. The apparatusof claim 16 further comprising a second spring to bias the sliding lockaway from the bottom wall of the housing.
 18. The apparatus of claim 12,wherein the trigger is movable along a first axis and the lockout ismovable along a second axis, the second axis perpendicular to the firstaxis.
 19. The apparatus of claim 12, wherein the trigger comprises abeveled surface that is to engage the lockout when the trigger isactivated to move the lockout in a direction that is perpendicular tothe movement of the trigger.
 20. An apparatus comprising: a housing toreceive a container having liquid to be used in an automated diagnosticanalyzer, the housing having a bottom wall, a side wall and an open top;a probe extending upward from the bottom wall toward the open top, theprobe to drain the liquid from the container when the probe is insertedinto the container; and a sliding lock slidably disposed within thehousing, the sliding lock comprising: an engagement surface disposedabove the probe; an opening in the engagement surface to receive theprobe therethrough when the sliding lock is moved toward the bottom wallof the housing; and a key slot, the sliding lock operable between alocked state in which movement of the sliding lock is prevented and anunlocked state in which the sliding lock is movable, wherein the slidinglock is switched to the unlocked state when a cap of the containerincludes a key corresponding to the key slot engages the key slot.
 21. Amethod comprising: inserting a container with a cap having a key ringinto a cradle, the cradle comprising: a housing; a probe disposed in thehousing; a sliding lock slidably disposed in the housing, the slidinglock having (1) an engagement surface, (2) an opening in the engagementsurface to receive the probe therethrough when the sliding lock is movedfrom a first position in which the engagement surface is above a tip ofthe probe to a second position in which the engagement surface is belowthe tip of the probe, and (3) a key slot in the engagement surface; anda lockout located below the engagement surface of the sliding lockreleaseably coupled to the sliding lock; moving the container into thecradle, wherein, if the key ring matches the key slot, the lockout ismoved between a locked position in which the sliding lock is preventedfrom moving in the housing and an unlocked position in which the slidinglock is movable in the housing to the second position; coupling thecontainer in the cradle; and draining the contents of the container viathe probe.
 22. The method of claim 21, wherein the container is invertedwhen the container is inserted into the cradle.
 23. The method of claim21, wherein the cradle further comprises a latch movable between anon-engaged position in which the container is moveable out of thecradle and an engaged position in which the container is coupled in thecradle.
 24. The method of claim 23 further comprising determining, via alatch position sensor, whether the latch is in the non-engaged positionor the engaged position.
 25. The method of claim 24 further comprisingdetermining, via a liquid level sensor, a level of liquid in thecontainer.
 26. The method of claim 25 further comprising actuating afirst indicator when the latch is determined to be in the engagedposition.
 27. The method of claim 26 further comprising actuating asecond indicator when the level of liquid in the container is determinedto be below a threshold.
 28. The method of claim 27, wherein the firstindicator is a first color light and the second indicator is a secondcolor light different than the first color light.
 29. The method ofclaim 27, wherein the first indicator and the second indicator aredisposed within a release button of the cradle.